HSDFDA Class 2 · 21 CFR 888.3690 · implantable

Prosthesis, Shoulder, Hemi-, Humeral, Metallic Uncemented

Device family · Orthopedic

Automated profile from regulatory + adverse-event registries · AI-reviewed · expert clinical sign-off in progress — not yet independently verified.
FDA clearances
71
Manufacturers
26
Flagged signals
15
Adverse-event reports
9,185

Code matrix

FDA product codeHSD
Device classClass 2
Regulation21 CFR 888.3690
GMDN— (crosswalk pending)
ImplantableYes
Life-sustainingNo

Adverse-event signals

Public · always free

MAUDE disproportionality (PRR), flagged where PRR ≥ 2, χ² ≥ 4, count ≥ 3.

Event typeYearReportsPRRχ²
Other20121587.51,199
Other20101481.71,038
Other2011740.8234
Other20141618.7251
Other2013317.532
Other20131011.787
Other2013910.568
Other2012910.568
Other201375.723
Other201564.915
Other201044.78
Injury201642.64
Injury202562.67
Injury201252.66
Injury2017162.113

Device-level recall linkage pending an FDA-recalls product-code re-ingest. Class 2 family · 9,185 total adverse-event reports.

Manufacturer landscape

ManufacturerClearancesLatestConcern
Howmedica Osteonics Corp.62007
ARTHREX, INC.52024
DEPUY ORTHOPAEDICS, INC.42008
Exactech, Inc.42013
Biomet, Inc.42005
Tornier32006
Intermedics Orthopedics31996
Tecres S.p.A.22011
Kirschner Medical Corp.21988
Arthrosurface, Inc.22018
FX SOLUTIONS22013
Depuy, Inc.21991
Ascension Orthopedics, Inc.22007
Howmedica Corp.21996
Synthes (Usa)12007
Wrightmedicaltechnologyinc11995
Zimmer GmbH12016
implantcast GmbH12020
Stryker Orthopaedics12005
Smith & Nephew, Inc.12012
Biocore9, LLC12020
Corin USA12002
ENDOTEC, INC.11999
Lima Corporate S.P.A.12012
Acu Med, Inc.12000

Concern score lights up where a maker maps to a scored entity (depth fast-follow).

Recent FDA clearances

Univers Revers CA Head and Adapter · Arthrex, Inc.510(k) · 2024-02-12
Univers Revers Humeral Cup Implant · Arthrex, Inc.510(k) · 2022-05-19
AGILON® XO Shoulder Replacement System · Implantcast GmbH510(k) · 2020-11-12
Biocore9 Humeral Resurfacing System · Biocore9, LLC510(k) · 2020-05-15
OVOMotion Shoulder Arthroplasty System · Arthrosurface, Inc.510(k) · 2018-04-18
Arthrex Univers Revers Shoulder Prosthesis System · Arthrex, Inc.510(k) · 2016-11-21
Anatomical Shoulder Domelock Dome centric · Zimmer GmbH510(k) · 2016-11-01
Arthrex Univers Revers CA Heads and Adapters · Arthrex, Inc.510(k) · 2016-04-19
HemiCAP Humeral Head XL (HHXL) Articular Resurfacing System · Arthrosurface, Inc.510(k) · 2014-12-19
EXACTECH EQUINOXE RESURFACING HUMERAL HEAD SYSTEM · Exactech, Inc.510(k) · 2013-11-26
HUMELOCK II CEMENTLESS SHOULDER SYSTEM · Fx Solutions510(k) · 2013-11-09
ARTHREX UNIVERS II CA HEADS · Arthrex, Inc.510(k) · 2013-10-30
SEVIIN SURFACE REPLACEMENT SHOULDER · Ingen Orthopedics, LLC510(k) · 2013-08-26
SMITH & NEPHEW, INC. SHOULDER SYSTEM INSTRUMENTS · Smith & Nephew, Inc.510(k) · 2012-09-07
SMR RESURFACING SHOULDER SYSTEM- HUMERAL HEADS, CTA HUMERAL HEADS · Lima Corporate S.P.A.510(k) · 2012-06-01
SPACER-S · Tecres S.P.A.510(k) · 2011-12-12
HUMELOCK CEMENTED SHOULDER PROSTHESIS · Fx Solutions510(k) · 2011-11-09
DEPUY GLOBAL AP CTA HUMERAL HEAD · DePuy Orthopaedics, Inc.510(k) · 2008-12-18
DEPUY GLOBAL C.AP. CTA RESURFACING SHOULDER · DePuy Orthopaedics, Inc.510(k) · 2008-08-08
DVO EXTENDED ARTICULATION HUMERAL HEADS · Dvo Extremity Solutions, LLC510(k) · 2008-02-19
SYNTHES (USA) EPOCA SHOULDER PROSTHESIS SYSTEM · Synthes (Usa)510(k) · 2007-11-28
ASCENSION HUMERAL RESURFACING ARTHOPLASTY (HRA) SYSTEM TPS/HA · Ascension Orthopedics, Inc.510(k) · 2007-06-22
REUNION HA FRACTURE STEM · Howmedica Osteonics Corp.510(k) · 2007-05-04
PROMOS MODULAR SHOULDER SYSTEM · Plus Orthopedics AG510(k) · 2007-03-02
AEQUALIS RESURFACING HEAD · Tornier510(k) · 2006-12-22

Sources: FDA 510(k)/PMA · openFDA MAUDE · FDA device classification · MedevIQ manufacturer-canonical. Registry data, AI-reviewed; expert clinical sign-off in progress.

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